Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885796 | 1.00 | ACHE (0.43) | ACHEALOX15ALOX12TRPA1ATM | |
| SCHEMBL9744264 | 0.86 | ACHE (0.58) | ACHEALOX15ALOX12TRPA1CYP3A4 | |
| SCHEMBL1755248 | 0.80 | NQO2 (0.38) | CYP3A4TDP1TSHRHPGDALDH1A1 | |
| SCHEMBL12189844 | 0.79 | CYP3A4 (0.43) | ALOX15ALOX12TRPA1CYP3A4TDP1 | |
| SCHEMBL11136759 | 0.79 | CYP3A4 (0.50) | ACHEALOX15ALOX12ATMCYP3A4 | |
| SCHEMBL18241199 | 0.75 | ALOX15 (0.36) | ALOX15ALOX12CYP3A4TDP1TSHR | |
| SCHEMBL31089099 | 0.75 | ALOX15 (0.36) | ALOX15ALOX12CYP3A4TDP1TSHR | |
| SCHEMBL27608122 | 0.75 | CYP3A4 (0.48) | ALOX15ALOX12CYP3A4TDP1TSHR | |
| SCHEMBL1697593 | 0.75 | ALDH1A1 (0.42) | ALOX15ALOX12CYP3A4TDP1TSHR | |
| SCHEMBL27642248 | 0.75 | ALOX15 (0.36) | ALOX15ALOX12CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032461-A1 | NITROGEN-CONTAINING FUSED RING COMPOUND | 武田薬品工業株式会社 (JP) | 2010-03-25 | — | — | WO | disclosed |
| EP-1227096-B1 | 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE | SATO PHARMA (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6525066-B2 | Bactericides; side effect reduction | SATO PHARMACEUTICAL CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20020173517-A1 | 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure | SATO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-21 | — | — | US | disclosed |
| EP-1227096-A1 | 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE | Sato Pharmaceutical Co. Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173517-A1 | 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure | IL4I1, TLR5, IFNG | ACHE 4632/4885ALOX15 364/4885ALOX12 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.