Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281553 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11277546 | 0.87 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11277549 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11283557 | 0.77 | SLC6A3 (0.40) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11159359 | 0.77 | MAPT (0.40) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11282680 | 0.77 | CES2 (0.49) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11142869 | 0.76 | MAPT (0.51) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11282926 | 0.75 | PRKAG1 (0.54) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11290112 | 0.75 | MDM2 (0.46) | ALDH1A1HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL11282000 | 0.74 | SLC6A2 (0.41) | ALDH1A1HPGDKMT2AESR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349618-A | 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-09-14 | — | — | US | claimed |
| US-4349618-A | 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-09-14 | — | — | US | disclosed |