Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.50 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.50 |
| ▸ | GGH | Q92820 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934928 | 0.84 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAGGHSMN1; SMN2 | |
| SCHEMBL28307549 | 0.84 | L3MBTL1 (0.42) | FOLH1NAALAD2RIMKLAMMP9 | |
| SCHEMBL8934926 | 0.84 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAGGHSMN1; SMN2 | |
| SCHEMBL34475333 | 0.83 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGGHSMN1; SMN2 | |
| SCHEMBL28212550 | 0.81 | MME (0.40) | SMN1; SMN2TDP1GAA | |
| SCHEMBL28432618 | 0.79 | MME (0.41) | SMN1; SMN2TDP1CYP1A2GAA | |
| SCHEMBL364062 | 0.76 | CPB2 (0.50) | FOLH1MMP9 | |
| SCHEMBL1604394 | 0.74 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGAA | |
| SCHEMBL28381301 | 0.73 | ALDH1A1 (0.49) | FOLH1GAAMMP8 | |
| SCHEMBL30645305 | 0.73 | ITGB2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389342-A | ARGININE, VALINE | PERIGNON INVESTMENTS, LTD. (KY) | 1983-06-21 | — | — | US | disclosed |
| US-4382920-A | HYPOTHERMIC AGENTS, DECREASED OXYGEN CONSUMPTION | PERIGNON INVESTMENTS LTD. (KY) | 1983-05-10 | — | — | US | disclosed |