Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148695 | 0.87 | NOD1 (0.50) | NOD1CYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL11146005 | 0.78 | NOD1 (0.53) | NOD1CYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL11148699 | 0.74 | NOD1 (0.52) | NOD1CYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL11156222 | 0.71 | NOD1 (0.48) | NOD1CYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL11198021 | 0.67 | NOD1 (0.51) | NOD1CYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL11248311 | 0.66 | NOD1 (0.42) | NOD1CYP2C9CYP2C19CYP1A2HTT | |
| SCHEMBL11241388 | 0.65 | ALDH3A1 (0.52) | NOD1HTTHSD17B10ALDH1A1HPGD | |
| SCHEMBL11196685 | 0.61 | CA2 (0.43) | NOD1CYP2C9CYP2C19CYP1A2KMT2A | |
| SCHEMBL3535449 | 0.60 | PPARG (0.56) | NOD1HTTHTR6HSD17B10ALDH1A1 | |
| SCHEMBL16818904 | 0.59 | ALDH3A1 (0.50) | NOD1HTTHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420479-A | 1-SUBSTITUTED, 2-AMINO-BENZIMIDAZOLES | ELI LILLY AND COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0091795-A1 | Olefinic benzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |