Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989246 | 0.76 | MAPT (0.58) | TSHRALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL29268200 | 0.76 | MAPT (0.58) | TSHRALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL7596545 | 0.71 | NAMPT (0.54) | LMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3531154 | 0.71 | PPARG (0.61) | PTGDR2PTGDRALDH1A1PPARGPPARA | |
| SCHEMBL3530028 | 0.70 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL29526316 | 0.69 | ALDH3A1 (0.50) | ALDH3A1LMNATSHRALDH1A1HTT | |
| SCHEMBL16818904 | 0.69 | ALDH3A1 (0.50) | ALDH3A1LMNATSHRALDH1A1HTT | |
| SCHEMBL23560752 | 0.68 | LMNA (0.67) | ALDH3A1LMNATSHRALDH1A1HTT | |
| SCHEMBL11248311 | 0.68 | NOD1 (0.42) | TSHRALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL16912860 | 0.67 | ALDH3A1 (1.00) | ALDH3A1LMNATSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |