Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | DRD4 | P21917 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241794 | 0.77 | ALDH1A1 (0.57) | NCF1ALDH1A1KDM4EHPGD | |
| SCHEMBL7295692 | 0.77 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1HSD17B10RAB9AMAOB | |
| SCHEMBL3588307 | 0.76 | ALDH1A1 (0.53) | DRD2DRD3NCF1ALDH1A1KDM4E | |
| SCHEMBL11321507 | 0.76 | ALDH1A1 (0.57) | NCF1ALDH1A1KDM4EHPGD | |
| SCHEMBL24524524 | 0.74 | KDM4E (0.77) | NCF1ALDH1A1HSD17B10RAB9AKDM4E | |
| SCHEMBL13149380 | 0.74 | CYP1A2 (0.77) | SIGMAR1ALDH1A1KDM4ELMNAMAOB | |
| SCHEMBL6194016 | 0.74 | HTR1A (0.64) | SIGMAR1DRD4DRD2DRD3NCF1 | |
| SCHEMBL1387431 | 0.73 | ALDH1A1 (0.62) | SIGMAR1DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL3560946 | 0.73 | HTR6 (0.53) | SIGMAR1NCF1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1415730 | 0.73 | SIGMAR1 (1.00) | SIGMAR1DRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382935-A | Analgesic drug containing a derivative of benzylpiperazine | Buzas, Andre (FR) | 1983-05-10 | — | — | US | claimed |
| EP-0034521-B1 | ANALGESIC DRUG CONTAINING 1-(3'-BENZOFURYL)-4-BENZYLPIPERAZINE AND PROCESS FOR ITS PREPARATION | Buzas, André (FR) | 1983-03-23 | — | — | EP | claimed |
| EP-0034521-A1 | Analgesic drug containing 1-(3'-benzofuryl)-4-benzylpiperazine and process for its preparation | Buzas, André (FR) | 1981-08-26 | — | — | EP | claimed |
| US-4382935-A | Analgesic drug containing a derivative of benzylpiperazine | Buzas, Andre (FR) | 1983-05-10 | — | — | US | disclosed |
| US-4382935-A | Analgesic drug containing a derivative of benzylpiperazine | Buzas, Andre (FR) | 1983-05-10 | — | — | US | disclosed |
| EP-0034521-B1 | ANALGESIC DRUG CONTAINING 1-(3'-BENZOFURYL)-4-BENZYLPIPERAZINE AND PROCESS FOR ITS PREPARATION | Buzas, André (FR) | 1983-03-23 | — | — | EP | disclosed |
| EP-0034521-B1 | ANALGESIC DRUG CONTAINING 1-(3'-BENZOFURYL)-4-BENZYLPIPERAZINE AND PROCESS FOR ITS PREPARATION | Buzas, André (FR) | 1983-03-23 | — | — | EP | disclosed |
| EP-0034521-A1 | Analgesic drug containing 1-(3'-benzofuryl)-4-benzylpiperazine and process for its preparation | Buzas, André (FR) | 1981-08-26 | — | — | EP | disclosed |
| EP-0034521-A1 | Analgesic drug containing 1-(3'-benzofuryl)-4-benzylpiperazine and process for its preparation | Buzas, André (FR) | 1981-08-26 | — | — | EP | disclosed |
| EP-0034521-A1 | Analgesic drug containing 1-(3'-benzofuryl)-4-benzylpiperazine and process for its preparation | Buzas, André (FR) | 1981-08-26 | — | — | EP | disclosed |