SCHEMBL11148071

SCHEMBL11148071

C1=CC2=Cc3ccccc3SC2=CN1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6528281 0.69 GPR84 (0.33) GPR84TRPA1
SCHEMBL29450353 0.69 GPR84 (0.33) GPR84TRPA1
SCHEMBL407792 0.68 DRD2 (0.33) TRPA1
SCHEMBL28653809 0.64 GPR84 (0.35) GPR84TRPA1
SCHEMBL11153228 0.63 L3MBTL1 (0.33)
SCHEMBL14807874 0.62 TRPA1 (0.34) TRPA1
SCHEMBL4742301 0.60 TRPA1 (0.50) GPR84TRPA1
SCHEMBL117715 0.60 TRPA1 (0.46) GPR84TRPA1
SCHEMBL29643017 0.59 GPR84 (0.37) GPR84TRPA1
SCHEMBL164600 0.57 PARP1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0035924-B1 BENZOTHIOPYRANO(2,3-C) PYRIDINES AND THEIR ACID ADDITION SALTS, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1983-08-03 EP claimed
EP-0035924-A1 Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1981-09-16 EP claimed
EP-0035924-B1 BENZOTHIOPYRANO(2,3-C) PYRIDINES AND THEIR ACID ADDITION SALTS, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1983-08-03 EP disclosed
EP-0035924-A1 Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1981-09-16 EP disclosed
EP-0035924-A1 Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1981-09-16 EP disclosed