Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658180 | 0.90 | KMT2A (0.41) | AKR1B1ALDH1A1KMT2AMAPK1HPGD | |
| SCHEMBL5409417 | 0.86 | PSMB8 (0.41) | AKR1B1MPOALDH1A1POLBHSPA5 | |
| SCHEMBL28545230 | 0.80 | TDP1 (0.53) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL5155762 | 0.80 | KMT2A (0.49) | KMT2ASIGMAR1TSHRMEN1MAPT | |
| SCHEMBL9186144 | 0.79 | AKR1B1 (0.37) | AKR1B1ALDH1A1POLBKMT2AHPGD | |
| SCHEMBL2450503 | 0.78 | KMT2A (0.57) | AKR1B1ALDH1A1KMT2AMAPK1HPGD | |
| SCHEMBL11142242 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ASIGMAR1CYP2D6MEN1 | |
| SCHEMBL11030785 | 0.78 | MGLL (0.51) | ALDH1A1KMT2AMAPK1HPGDMGLL | |
| SCHEMBL7314478 | 0.76 | HTR1A (0.47) | ALDH1A1KMT2AMAPK1HPGDKDM4E | |
| SCHEMBL499428 | 0.75 | KMT2A (0.46) | ALDH1A1KMT2AMAPK1HPGDPARL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217575-B2 | Avidin derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-05-15 | — | — | US | disclosed |
| US-4401594-A | PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | disclosed |