Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313392 | 0.87 | TAAR1 (0.43) | TAAR1P2RX7POLBMAPK1SLC6A2 | |
| SCHEMBL4267814 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL24911005 | 0.79 | CA2 (0.41) | TAAR1P2RX7POLBMAPK1SLC6A2 | |
| SCHEMBL13856265 | 0.79 | TAAR1 (0.39) | TAAR1P2RX7SMN1; SMN2CTSSNOS3 | |
| SCHEMBL5407429 | 0.79 | SLC6A2 (0.43) | TAAR1P2RX7SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL25771233 | 0.79 | GABRA1 (0.46) | TAAR1POLBMAPK1SLC6A2SLC6A4 | |
| SCHEMBL19658016 | 0.79 | GABRA1 (0.47) | TAAR1P2RX7SLC6A2SLC6A4MC4R | |
| SCHEMBL16939396 | 0.78 | P2RX7 (0.41) | TAAR1P2RX7CTSSCTSK | |
| SCHEMBL24450927 | 0.78 | GABRA1 (0.40) | TAAR1P2RX7POLBMAPK1SMN1; SMN2 | |
| SCHEMBL11150461 | 0.78 | NOS3 (0.39) | TAAR1P2RX7POLBSMN1; SMN2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404220-A | INSECTIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4299772-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |