Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LIPA | P38571 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607576 | 0.69 | LIPA (1.00) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL17078253 | 0.69 | LIPA (1.00) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL17078239 | 0.69 | LIPA (1.00) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL22978691 | 0.68 | TSHR (0.49) | ALDH1A1POLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28673249 | 0.68 | KMT2A (0.62) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL30473912 | 0.68 | ALDH1A1 (0.56) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL30449933 | 0.67 | ALDH1A1 (0.50) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL28864240 | 0.67 | ALDH1A1 (0.76) | ALDH1A1POLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31718378 | 0.67 | ALDH1A1 (0.55) | ALDH1A1POLBLIPAKMT2ASMN1; SMN2 | |
| SCHEMBL30443406 | 0.67 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075141-A1 | 1,2,5-Oxadiazole-3,4-dicarboxylic-acid derivatives, process for their production, their use and pharmaceutical preparations containing them | CASSELLA Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |