Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875579 | 0.73 | TMPRSS15 (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL27361867 | 0.73 | RAB9A (0.49) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL13631422 | 0.72 | KMT2A (0.66) | TSHRALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL6632393 | 0.72 | TMPRSS15 (0.55) | ALDH1A1POLBSMN1; SMN2MAPTHTT | |
| SCHEMBL9844093 | 0.70 | TMPRSS15 (0.47) | ALDH1A1SMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL22978714 | 0.70 | ALDH1A1 (0.51) | TSHRALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL19520914 | 0.69 | TMPRSS15 (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL1532836 | 0.69 | ALDH1A1 (0.50) | TSHRALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL11150108 | 0.68 | ALDH1A1 (0.53) | TSHRALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL27952188 | 0.68 | TMPRSS15 (0.45) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026803-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |