Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221088 | 0.89 | TSHR (0.59) | TSHRPMP22LMNABLMKDM4E | |
| SCHEMBL11143530 | 0.89 | ALDH1A1 (0.51) | TSHRPMP22LMNABLMKDM4E | |
| SCHEMBL11148605 | 0.85 | ALDH1A1 (0.55) | TSHRPMP22LMNABLMKDM4E | |
| SCHEMBL9319737 | 0.84 | ALDH1A1 (0.66) | TSHRPMP22LMNABLMKDM4E | |
| Hydrochloric Acid SCHEMBL11012829 | 0.83 | ALDH1A1 (0.64) | TSHRPMP22LMNABLMKDM4E | |
| SCHEMBL11154687 | 0.82 | LMNA (0.46) | TSHRPMP22LMNABLMKDM4E | |
| SCHEMBL11147216 | 0.80 | ADORA2A (0.43) | TSHRPMP22LMNABLMKDM4E | |
| Cinoxacin SCHEMBL29471771 | 0.79 | KDM4E (1.00) | TSHRPMP22LMNABLMKDM4E | |
| Cinoxacin SCHEMBL43770 | 0.79 | KDM4E (1.00) | TSHRPMP22LMNABLMKDM4E | |
| Cinoxacin SCHEMBL28034323 | 0.78 | KDM4E (0.97) | TSHRPMP22LMNABLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |