Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191668 | 0.83 | ATM (0.50) | ATMTLR4TLR2AKR1C3MEN1 | |
| SCHEMBL11034780 | 0.81 | ATM (0.49) | ATMTLR4TLR2AKR1C3MEN1 | |
| SCHEMBL11209703 | 0.80 | MAOB (0.47) | ATMTLR4TLR2AKR1C3MEN1 | |
| SCHEMBL9014614 | 0.76 | TLR4 (0.49) | ATMTLR4TLR2AKR1C3MEN1 | |
| SCHEMBL27900292 | 0.71 | TLR4 (0.64) | TLR4TLR2MAOBALOX5PTGS1 | |
| SCHEMBL4553033 | 0.71 | TLR4 (0.54) | ATMTLR4TLR2AKR1C3MEN1 | |
| SCHEMBL20472367 | 0.71 | ALDH1A1 (0.59) | ATMTLR4TLR2MEN1KMT2A | |
| SCHEMBL10550570 | 0.71 | ALDH1A1 (0.47) | ATMTLR4TLR2MEN1KMT2A | |
| SCHEMBL10547225 | 0.71 | ALDH1A1 (0.51) | ATMTLR4TLR2MEN1KMT2A | |
| SCHEMBL10545617 | 0.71 | RELA (0.51) | ATMMAOBLTA4HALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401673-A | INSECTIDICES; NEMATOCIDES; MITICIDES; SKIN DISORDERS | ROUSSEL UCLAF (FR) | 1983-08-30 | — | — | US | disclosed |