Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150720 | 0.80 | ATM (0.46) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL9014614 | 0.79 | TLR4 (0.49) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL191668 | 0.79 | ATM (0.50) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL11034780 | 0.77 | ATM (0.49) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL2658166 | 0.77 | ALDH1A1 (0.38) | MAOBLMNATSHRALDH1A1AKR1C3 | |
| SCHEMBL1218847 | 0.76 | TLR4 (0.53) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL27900292 | 0.74 | TLR4 (0.64) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL4553033 | 0.74 | TLR4 (0.54) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL10570523 | 0.73 | TLR4 (0.50) | MAOBTLR4TLR2ALOX5PTGS1 | |
| SCHEMBL15177159 | 0.73 | TLR4 (0.58) | MAOBTLR4TLR2ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0008333-A1 | Alpha-prop-1-ynyl-3-phenoxybenzyl alcohols, their preparation and use as intermediate products in the preparation of pesticides | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |