Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441427 | 0.83 | MMP1 (0.49) | KMT2AALDH1A1F10LMNAL3MBTL1 | |
| SCHEMBL6943126 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1F10LMNASMN1; SMN2 | |
| SCHEMBL11151507 | 0.74 | KMT2A (0.44) | KMT2AALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL11148255 | 0.74 | GAA (0.41) | KMT2AALDH1A1KCNH2 | |
| SCHEMBL11147204 | 0.73 | NPSR1 (0.38) | LMNAL3MBTL1SMN1; SMN2LTA4HEPHX2 | |
| SCHEMBL11247290 | 0.73 | NPSR1 (0.55) | KMT2AALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12045402 | 0.73 | ALPL (0.47) | LMNAL3MBTL1SMN1; SMN2KCNH2HSP90AA1 | |
| SCHEMBL11151952 | 0.73 | FFAR1 (0.46) | KMT2AALDH1A1F10SMN1; SMN2 | |
| SCHEMBL11147256 | 0.72 | LMNA (0.42) | KMT2AALDH1A1LMNAL3MBTL1LTA4H | |
| SCHEMBL11147242 | 0.72 | MMP1 (0.48) | KMT2AALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-B1 | BASIC PHENYL ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION OF THESE ETHERS AND COMPOSITIONS | MERCK PATENT GmbH (DE) | 1983-08-10 | — | — | EP | disclosed |
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |