Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534322 | 0.84 | MBTD1 (0.39) | NOTUMMAPTLMNAKCNH2HTR3E | |
| SCHEMBL29140942 | 0.79 | NOTUM (0.37) | NOTUMMAPTLMNAKCNH2HTR3E | |
| SCHEMBL28170358 | 0.73 | BPTF (0.33) | BPTFNOTUMMAPTLMNA | |
| SCHEMBL7627338 | 0.73 | — | — | |
| SCHEMBL1241881 | 0.69 | CYP2D6 (0.33) | KCNH2 | |
| SCHEMBL29163640 | 0.69 | NOTUM (0.39) | NOTUMMAPTKCNH2HTR3EHTR3B | |
| SCHEMBL31550557 | 0.69 | ADRB1 (0.37) | MAPTADRB1L3MBTL3L3MBTL1 | |
| SCHEMBL9038390 | 0.69 | ALDH1A1 (0.39) | HSD17B10 | |
| SCHEMBL28740969 | 0.66 | HTR3E (0.41) | MAPTLMNARAB9AHTR3EHTR3B | |
| SCHEMBL10845510 | 0.66 | G6PD (0.42) | L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58131969-A | — | — | None | — | — | JP | disclosed |
| JP-S58131969-A | 2-PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1983-08-06 | — | — | JP | disclosed |