Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BCKDK | O14874 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | EPM2A | O95278 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421246 | 0.87 | G6PD (0.47) | G6PDTLR9KDM4EALDH1A1MAPT | |
| SCHEMBL11574705 | 0.85 | KDM4E (0.47) | G6PDTLR9KDM4EALDH1A1MAPT | |
| SCHEMBL11153439 | 0.84 | KIF11 (0.49) | G6PDTLR9KDM4EALDH1A1MAPT | |
| SCHEMBL2810528 | 0.83 | KDM4E (0.58) | G6PDTLR9KDM4EALDH1A1MAPT | |
| SCHEMBL30369262 | 0.83 | KDM4E (0.58) | G6PDTLR9KDM4EALDH1A1MAPT | |
| SCHEMBL4514959 | 0.82 | ALDH1A1 (0.52) | G6PDKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL31344216 | 0.82 | ALDH1A1 (0.52) | G6PDKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4731621 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTLMNAPOLB | |
| SCHEMBL29441239 | 0.78 | KDM4E (0.61) | G6PDTLR9KDM4EMAPTLMNA | |
| SCHEMBL472579 | 0.78 | KDM4E (0.61) | G6PDTLR9KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005607-B1 | XANTHONE AND THIOXANTHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KEFALAS A/S (DK) | 1983-10-26 | — | — | EP | disclosed |