Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162983 | 0.85 | PLK1 (0.53) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL11166459 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPSR1ALOX12GPR55MEN1 | |
| SCHEMBL11171128 | 0.82 | F10 (0.43) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL11158176 | 0.76 | NPSR1 (0.57) | ALDH1A1NPSR1ALOX12GPR55MEN1 | |
| SCHEMBL11166925 | 0.76 | NPSR1 (0.62) | ALDH1A1NPSR1ALOX12GPR55MEN1 | |
| SCHEMBL11158092 | 0.75 | ALDH1A1 (0.52) | ALDH1A1NPSR1ALOX12GPR55ACLY | |
| SCHEMBL11159755 | 0.73 | ALDH1A1 (0.51) | ALDH1A1NPSR1ALOX12GPR55MEN1 | |
| SCHEMBL7815135 | 0.73 | ADRA2C (0.59) | ALDH1A1NPSR1ALOX12GPR55CA12 | |
| SCHEMBL11153739 | 0.73 | ADRA2A (0.42) | NPSR1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL11160995 | 0.72 | CACNA1H (0.49) | ALDH1A1NPSR1ALOX12GPR55MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |