Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 9/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618910 | 0.78 | PLA2G7 (0.71) | PLA2G7 | |
| SCHEMBL10736202 | 0.76 | GFER (0.57) | GFERHPGDPLA2G7LMNAL3MBTL1 | |
| SCHEMBL10670202 | 0.75 | DAO (0.49) | DAOLMNA | |
| SCHEMBL11160293 | 0.75 | HPGD (0.46) | GFERHPGDPLA2G7DAOL3MBTL1 | |
| SCHEMBL10622845 | 0.72 | PLA2G7 (0.56) | GFERHPGDPLA2G7DAOLMNA | |
| SCHEMBL9224582 | 0.72 | PNP (0.70) | GFERHPGDPLA2G7 | |
| SCHEMBL10622902 | 0.71 | LMNA (0.76) | GFERHPGDPLA2G7DAOLMNA | |
| SCHEMBL7371310 | 0.69 | ALDH1A1 (0.50) | GFERHPGDPLA2G7DAO | |
| SCHEMBL10731082 | 0.68 | PLA2G7 (0.54) | GFERHPGDPLA2G7DAOLMNA | |
| Hydrochloric Acid SCHEMBL7377500 | 0.68 | ALDH1A1 (0.49) | GFERHPGDPLA2G7DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374836-A | Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES LTD. (GB) | 1983-02-22 | — | — | US | disclosed |
| US-4220767-A | HISTAMINE ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-09-02 | — | — | US | disclosed |
| EP-0010894-A1 | Antisecretory heterocyclic guanidine derivatives, process for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-05-14 | — | — | EP | disclosed |
| US-4185103-A | ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |