Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.52 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162874 | 0.83 | DRD2 (0.55) | HTR2AHTR1ADRD2MAPTHTR7 | |
| SCHEMBL11170405 | 0.83 | MAPT (0.62) | HTR2AHTR1ADRD2HTR2CMAPT | |
| SCHEMBL23287628 | 0.79 | MAPT (0.52) | DRD2MAPT | |
| SCHEMBL11165829 | 0.78 | DRD2 (0.62) | HTR2AHTR1ADRD2MAPTHTR7 | |
| SCHEMBL4383912 | 0.77 | JAK2 (0.68) | — | |
| SCHEMBL9742938 | 0.75 | MEN1 (0.70) | MAPT | |
| SCHEMBL11169527 | 0.75 | DRD2 (0.58) | HTR1ADRD2MAPTHTR7 | |
| SCHEMBL11169258 | 0.74 | DRD2 (0.57) | HTR1ADRD2MAPTHTR7 | |
| SCHEMBL23097600 | 0.74 | HTR1A (0.66) | HTR2AHTR1ADRD2MAPTRAB9A | |
| SCHEMBL14378834 | 0.74 | PTPN1 (0.64) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | claimed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | claimed |
| JP-56118046-A | — | — | None | — | — | JP | disclosed |
| JP-S56118046-A | PROPANE DERIVATIVE AND ITS PREPARATION | TANABE SEIYAKU CO LTD | 1981-09-16 | — | — | JP | disclosed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | disclosed |