Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11161262 | 0.83 | HTR2A (0.56) | MAPTHTR2ADRD3HTR1ADRD2 | |
| SCHEMBL11165829 | 0.78 | DRD2 (0.62) | MAPTALDH1A1HTR2AHPGDHTR1A | |
| SCHEMBL11169527 | 0.75 | DRD2 (0.58) | MAPTALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL11162874 | 0.75 | DRD2 (0.55) | MAPTALDH1A1HTR2AHPGDHTR1A | |
| SCHEMBL10900785 | 0.75 | MAPT (0.55) | MAPTTSHRALDH1A1HTTHTR2A | |
| SCHEMBL11169258 | 0.74 | DRD2 (0.57) | MAPTALDH1A1HPGDHTR1ADRD2 | |
| SCHEMBL23097600 | 0.74 | HTR1A (0.66) | MAPTALDH1A1HTTHTR2ADRD3 | |
| SCHEMBL8205948 | 0.74 | DRD2 (0.56) | MAPTTSHRHRH3HPGDRECQL | |
| SCHEMBL813535 | 0.74 | HPGD (0.79) | MAPTALDH1A1HTTHPGDRECQL | |
| Piperamide SCHEMBL635749 | 0.73 | HTR7 (0.61) | MAPTALDH1A1HTTHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |