Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165829 | 0.86 | DRD2 (0.62) | DRD2HTR7TP53MAPTHTR2A | |
| SCHEMBL11169527 | 0.83 | DRD2 (0.58) | DRD2HTR7TP53MAPTUSP2 | |
| SCHEMBL11161262 | 0.83 | HTR2A (0.56) | DRD2HTR7MAPTHTR2AHTR1A | |
| SCHEMBL11169258 | 0.83 | DRD2 (0.57) | DRD2HTR7TP53MAPTUSP2 | |
| SCHEMBL11167712 | 0.81 | MCHR1 (0.63) | DRD2HTR7TP53MAPTUSP2 | |
| SCHEMBL11160725 | 0.78 | ALDH1A1 (0.55) | DRD2TP53MAPTUSP2ALDH1A1 | |
| SCHEMBL11173613 | 0.78 | MCHR1 (0.66) | DRD2TP53MAPTUSP2ALDH1A1 | |
| SCHEMBL11168272 | 0.78 | DRD2 (0.56) | DRD2MAPTHTR2AUSP2ALDH1A1 | |
| SCHEMBL11198528 | 0.78 | ALDH1A1 (0.60) | TP53MAPTUSP2ALDH1A1LMNA | |
| SCHEMBL11159508 | 0.77 | MAPT (0.55) | TP53MAPTUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | claimed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | claimed |
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | disclosed |