Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170252 | 0.81 | NPC1 (0.40) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL11160179 | 0.78 | LMNA (0.35) | LMNAADORA2BCCNE1CDK2PDE4A | |
| SCHEMBL4892136 | 0.78 | LMNA (0.35) | LMNAADORA2BCCNE1CDK2PDE4A | |
| SCHEMBL11167289 | 0.76 | ALDH1A1 (0.39) | LMNAADORA2B | |
| SCHEMBL11169323 | 0.74 | CYP3A4 (0.38) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11163016 | 0.70 | SMN1; SMN2 (0.44) | LMNA | |
| SCHEMBL11174630 | 0.70 | — | — | |
| SCHEMBL12894756 | 0.68 | ALB (0.43) | LMNAADORA2BHSD17B10ADORA2AADORA1 | |
| SCHEMBL11166828 | 0.66 | ALDH1A1 (0.41) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1225207 | 0.65 | AGBL2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4395406-A | 5-Halopyrimid-2-ones | NYEGAARD & CO. A/S (NO) | 1983-07-26 | — | — | US | claimed |
| US-4395406-A | 5-Halopyrimid-2-ones | NYEGAARD & CO. A/S (NO) | 1983-07-26 | — | — | US | disclosed |