Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491422 | 0.80 | HTR3E (0.53) | ITGB3ITGAVNOS3NOS1TDP1 | |
| SCHEMBL15726519 | 0.78 | NPC1 (0.42) | NOS3NOS1MAPTMEN1KMT2A | |
| SCHEMBL1116457 | 0.77 | AHR (0.41) | — | |
| SCHEMBL1116531 | 0.76 | NOS3 (0.36) | NOS3NOS1MAPTMEN1KMT2A | |
| SCHEMBL20651366 | 0.73 | MAPT (0.36) | NOS3NOS1MAPTMEN1KMT2A | |
| SCHEMBL14609835 | 0.72 | SLC6A4 (0.36) | MAPTHPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL12028610 | 0.72 | HPGD (0.36) | MAPTMEN1KMT2AGAAHPGD | |
| SCHEMBL24456244 | 0.71 | NOS1 (0.48) | ITGB3ITGAVNOS3NOS1SIGMAR1 | |
| SCHEMBL1116448 | 0.70 | HTR3E (0.61) | ITGB3ITGAVNOS3NOS1MAPT | |
| SCHEMBL6071851 | 0.68 | HPGD (0.47) | MEN1KMT2AGAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280932-B1 | Process for preparing substituted biphenylanilides | BAYER IP GMBH (DE) | 2017-10-18 | — | — | EP | claimed |
| EP-2473476-B1 | Tetraarylborate method for producing substituted biphenyls | BAYER IP GMBH (DE) | 2015-01-14 | — | — | EP | claimed |
| US-8455689-B2 | Process for preparing substituted biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2013-06-04 | — | — | US | claimed |
| US-8436211-B2 | Tetraarylborate process for the preparation of substituted biphenyls | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | claimed |
| EP-2473476-A1 | TETRAARYLBORATE PROCESS FOR PRODUCING SUBSTITUTED BIPHENYLS | Bayer CropScience AG (DE) | 2012-07-11 | — | — | EP | claimed |
| US-20110105796-A1 | Tetraarylborate Process for the Preparation of Substituted Biphenyls | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | claimed |
| US-20110092736-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | US | claimed |
| WO-2011023324-A1 | TETRAARYLBORATE PROCESS FOR PRODUCING SUBSTITUTED BIPHENYLS | BAYER CROPSCIENCE AG (DE) | 2011-03-03 | — | — | WO | claimed |
| EP-2280932-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | Bayer CropScience AG (DE) | 2011-02-09 | — | — | EP | claimed |
| EP-2119697-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-11-18 | — | — | EP | claimed |
| WO-2009135598-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG | 2009-11-12 | — | — | WO | claimed |
| EP-2280932-B1 | Process for preparing substituted biphenylanilides | BAYER IP GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-2473476-B1 | Tetraarylborate method for producing substituted biphenyls | BAYER IP GMBH (DE) | 2015-01-14 | — | — | EP | disclosed |
| US-8455689-B2 | Process for preparing substituted biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2013-06-04 | — | — | US | disclosed |
| US-8436211-B2 | Tetraarylborate process for the preparation of substituted biphenyls | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20110092736-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | US | disclosed |
| WO-2011023324-A1 | TETRAARYLBORATE PROCESS FOR PRODUCING SUBSTITUTED BIPHENYLS | BAYER CROPSCIENCE AG (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-2280932-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | Bayer CropScience AG (DE) | 2011-02-09 | — | — | EP | disclosed |
| EP-2119697-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2009135598-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105796-A1 | Tetraarylborate Process for the Preparation of Substituted Biphenyls | AHR, DDT, CYP4F3 | ITGB3 901/4885ITGAV 1851/4885NOS3 4637/4885 |
| US-20110092736-A1 | Process for Preparing Substituted Biphenylanilides | CYP1B1, DDT, ABL1 | ITGB3 1671/4885ITGAV 3549/4885NOS3 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.