Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769428 | 0.80 | KDM4E (0.48) | CYP3A4NPY5RALDH1A1CYP1A2KMT2A | |
| SCHEMBL11481381 | 0.79 | NPY5R (0.48) | CYP11B1CYP11B2CYP2A6CYP3A4NPY5R | |
| SCHEMBL9741082 | 0.75 | NPY5R (0.51) | CYP2A6CYP3A4NPY5RALDH1A1CYP1A2 | |
| SCHEMBL7367947 | 0.74 | NPY5R (0.63) | CYP11B1CYP11B2NPY5RALDH1A1KMT2A | |
| SCHEMBL7370892 | 0.74 | NPY5R (0.57) | CYP11B1CYP11B2CYP2A6CYP3A4NPY5R | |
| SCHEMBL7365631 | 0.74 | CYP11B1 (0.53) | CYP11B1CYP11B2NPY5RALDH1A1KMT2A | |
| SCHEMBL11267958 | 0.74 | MAPK14 (0.50) | CYP11B1CYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL20752459 | 0.72 | NPY5R (0.64) | CYP11B1CYP11B2CYP2A6CYP3A4NPY5R | |
| SCHEMBL7369715 | 0.72 | CYP11B1 (0.52) | CYP11B1CYP11B2NPY5RALDH1A1KMT2A | |
| SCHEMBL7366319 | 0.72 | NPY5R (0.64) | CYP11B1CYP11B2NPY5RALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280984-A2 | SULFATED GALACTANS WITH ANTITHROMBOTIC ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING OR PROPHYLAXIS OF ARTERIAL OR VENOUS THROMBOSIS, METHOD OF EXTRACTION AND USE THEREOF | S.A. Delta Do Prata (BR) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009137899-A2 | SULFATED GALACTANS WITH ANTITHROMBOTIC ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING OR PROPHYLAXIS OF ARTERIAL OR VENOUS THROMBOSIS, METHOD OF EXTRACTION AND USE THEREOF | S.A. DELTA DO PRATA (BR) | 2009-11-19 | — | — | WO | disclosed |