Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367947 | 0.86 | NPY5R (0.63) | NPY5RMGAMGAASIMGAM2 | |
| SCHEMBL7375046 | 0.85 | NPY5R (0.55) | NPY5RMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL20425689 | 0.84 | GAA (0.58) | NPY5RMGAMGAASIMGAM2 | |
| SCHEMBL13115243 | 0.83 | NPY5R (0.57) | NPY5RMGAMGAASIMGAM2 | |
| SCHEMBL7367787 | 0.83 | ROS1 (0.48) | NPY5RCYP11B1CYP11B2KMT2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL23736197 | 0.83 | GAA (0.57) | NPY5RMGAMGAASIMGAM2 | |
| SCHEMBL13115329 | 0.81 | CYP11B1 (0.46) | NPY5RCYP11B1CYP11B2KMT2ACYP19A1 | |
| SCHEMBL27674785 | 0.80 | CYP11B1 (0.48) | NPY5RCYP11B1CYP11B2CYP19A1KDM4E | |
| SCHEMBL4113640 | 0.79 | PIN1 (0.64) | NPY5RMGAMGAASIMGAM2 | |
| SCHEMBL7370256 | 0.79 | AMY1A (0.46) | NPY5RCYP11B1CYP11B2KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |