SCHEMBL1116595

SCHEMBL1116595

CCCCN(CCCC)CCCCO[SiH3]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
KDM5A P29375 2/20 0.35
HTR1B P28222 1/20 0.35
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
GAA P10253 1/20 0.34
CYP2D6 P10635 1/20 0.34
DRD3 P35462 1/20 0.34
SCN1A P35498 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7751913 0.98 THRA (0.38) THRATHRBKDM5ABCHEACHE
SCHEMBL87880 0.95 DNM1 (0.39) THRATHRBKDM5ADNM1PHF8
SCHEMBL6552697 0.91 MAOA (0.36) BCHEACHE
SCHEMBL20394629 0.88 HTR1B (0.40) THRATHRBKDM5AHTR1BLMNA
SCHEMBL6552248 0.83 ALDH1A1 (0.43)
SCHEMBL9773573 0.82 CA12 (0.39) KDM5AHTR1BLMNACYP1A2CHRM2
SCHEMBL74063 0.79
SCHEMBL11350672 0.79 DNM1 (0.47) THRBKDM5ALMNAKCNH2DNM1
Trimethylammonium SCHEMBL27893406 0.77 DNM1 (0.38) THRBDNM1
SCHEMBL1389233 0.76 THRB (0.50) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2309333-B1 TONER CANON KK (JP) 2017-03-01 EP disclosed
EP-2281778-B1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER CANON KK (JP) 2016-08-31 EP disclosed
US-8084174-B2 Toner CANON KABUSHIKI KAISHA (JP) 2011-12-27 US disclosed
EP-2309333-A1 TONER Canon Kabushiki Kaisha (JP) 2011-04-13 EP disclosed
EP-2281778-A1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER Canon Kabushiki Kaisha (JP) 2011-02-09 EP disclosed
US-7811734-B2 Hydrophobic inorganic fine particles and toner CANON KABUSHIKI KAISHA (JP) 2010-10-12 US disclosed
US-20100028793-A1 TONER CANON KABUSHIKI KAISHA (JP) 2010-02-04 US disclosed
US-20100009277-A1 HYDROPHOBIC INORGANIC FINE PARTICLES AND TONER CANON KABUSHIKI KAISHA (JP) 2010-01-14 US disclosed
US-20090242847-A1 DISPLAY PARTICLES FOR IMAGE DISPLAY APPARATUS AND IMAGE DISPLAY APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-10-01 US disclosed