Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.46 |
| ▸ | AGXT | P21549 | 5/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003582 | 0.86 | IDO1 (0.45) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL11170284 | 0.73 | DPP4 (0.39) | IDO1DPP4DPP8DPP9FAP | |
| SCHEMBL11006655 | 0.73 | CTSL (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL11159698 | 0.70 | IDO1 (0.56) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL11010247 | 0.69 | OPRK1 (0.41) | MAOBMAOA | |
| SCHEMBL11160529 | 0.68 | DPP4 (0.41) | IDO1AGXTDPP4DPP8SIGMAR1 | |
| SCHEMBL11167252 | 0.68 | KMT2A (0.39) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL11157958 | 0.68 | AGXT (0.53) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL1520590 | 0.67 | IDO1 (1.00) | IDO1AGXTMAOB | |
| SCHEMBL11165396 | 0.67 | IDO1 (0.57) | IDO1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |