Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 12/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007326 | 0.93 | DPP4 (0.40) | DPP4DPP8DPP9FAPKDM4E | |
| SCHEMBL11157958 | 0.76 | AGXT (0.53) | DPP4DPP8DPP9FAPIDO1 | |
| SCHEMBL11006819 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL11165396 | 0.74 | IDO1 (0.57) | DPP4DPP8DPP9FAPIDO1 | |
| SCHEMBL1669101 | 0.74 | IDO1 (0.57) | IDO1 | |
| SCHEMBL11166191 | 0.73 | IDO1 (0.46) | DPP4DPP8DPP9FAPIDO1 | |
| Hydrochloric Acid SCHEMBL11010682 | 0.73 | IDO1 (0.59) | IDO1 | |
| SCHEMBL11006655 | 0.72 | CTSL (0.49) | DPP4DPP8DPP9FAP | |
| SCHEMBL11167676 | 0.71 | AGXT (0.55) | DPP4DPP8DPP9FAPIDO1 | |
| SCHEMBL11165500 | 0.69 | IDO1 (0.44) | DPP4DPP8DPP9FAPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |