Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | BCL6 | P41182 | 2/20 | 0.37 |
| ▸ | BCOR | Q6W2J9 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716987 | 0.94 | MAPT (0.48) | MAPTGLABCL6BCORLMNA | |
| SCHEMBL10756290 | 0.94 | MAPT (0.48) | MAPTGLABCL6BCORLMNA | |
| SCHEMBL10892179 | 0.89 | MAPT (0.46) | MAPTGLALMNAPKMMEN1 | |
| SCHEMBL111665 | 0.88 | MAPT (0.54) | MAPTGLABCL6BCORLMNA | |
| SCHEMBL30100539 | 0.88 | MAPT (0.54) | MAPTGLABCL6BCORLMNA | |
| SCHEMBL10758961 | 0.88 | MAPT (0.54) | MAPTGLABCL6BCORLMNA | |
| SCHEMBL1741987 | 0.82 | ALDH1A1 (0.54) | MAPTLMNAPKMMEN1POLB | |
| SCHEMBL11048215 | 0.82 | MAPT (0.52) | MAPTGLALMNAPKMMEN1 | |
| SCHEMBL8099339 | 0.79 | MAPT (0.58) | MAPTBCL6BCORLMNAPKM | |
| SCHEMBL10442762 | 0.79 | MEN1 (0.52) | MAPTGLALMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099242-A1 | COSMETIC AGENTS CONTAINING PROTEIN DISULFIDE ISOMERASE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-12-04 | — | — | WO | claimed |
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | claimed |
| EP-0867170-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | claimed |
| EP-0708634-B1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KGAA (DE) | 1997-09-03 | — | — | EP | claimed |
| EP-0708634-A1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KGAA (DE) | 1996-05-01 | — | — | EP | claimed |
| WO-1995001713-A1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-01-19 | — | — | WO | claimed |
| EP-0132568-B1 | DERIVATIVES OF 1,4-DIAMINO-5-CHLORO-2-NITROBENZENE, PROCESS FOR THEIR PRODUCTION AND AGENTS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0132568-A1 | Derivatives of 1,4-diamino-5-chloro-2-nitrobenzene, process for their production and agents for dyeing hair | Wella Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | claimed |
| EP-2705094-B1 | DISULFIDE DYES | BASF SE (DE) | 2021-12-15 | — | — | EP | disclosed |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2017-09-28 | — | — | US | disclosed |
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | ALFA PARF GROUP S.P.A. (IT) | 2016-09-01 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| EP-0708634-A1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KGAA (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001713-A1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-01-19 | — | — | WO | disclosed |
| WO-1995001713-A1 | DYES CONTAINING TETRAAMINOPYRIMIDINE AND DIRECT-DYEING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-01-19 | — | — | WO | disclosed |
| US-4704474-A | RED-TO-VIOLET DIRECT DYES | WELLA AKTIENGESELLSCHAFT (DE) | 1987-11-03 | — | — | US | disclosed |
| EP-0132568-B1 | DERIVATIVES OF 1,4-DIAMINO-5-CHLORO-2-NITROBENZENE, PROCESS FOR THEIR PRODUCTION AND AGENTS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0132568-A1 | Derivatives of 1,4-diamino-5-chloro-2-nitrobenzene, process for their production and agents for dyeing hair | Wella Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | KRT18, FABP2, CPT1A | MAPT 172/4885GLA 2694/4885BCL6 163/4885 |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | KRT18, GRHPR, CUTA | MAPT 565/4885GLA 4/4885BCL6 3252/4885 |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | MAPT 2715/4885GLA 26/4885BCL6 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.