Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.38 |
| ▸ | RXRB | P28702 | 6/20 | 0.34 |
| ▸ | RXRG | P48443 | 5/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167948 | 0.71 | OPRM1 (0.43) | RXRA | |
| SCHEMBL4407340 | 0.69 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9520091 | 0.68 | RXRA (0.43) | RXRACYP2D6 | |
| SCHEMBL10842211 | 0.66 | RXRA (0.38) | RXRARXRBAKR1C3AKR1C2 | |
| SCHEMBL10842199 | 0.66 | GAA (0.47) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL2321735 | 0.65 | HSD11B1 (0.59) | LMNA | |
| SCHEMBL8522801 | 0.65 | RXRA (0.60) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL10335841 | 0.64 | ADRA2A (0.35) | RXRALMNA | |
| SCHEMBL9587601 | 0.63 | CYP26A1 (0.38) | RXRARARBRARARARGCYP26B1 | |
| SCHEMBL1335906 | 0.63 | ESR2 (0.48) | CYP3A4APPCYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072042-A | Skin disorders, anticarcinogenic-antitumor agent | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |