Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 5/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.55 |
| ▸ | NAAA | Q02083 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 7/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008420 | 0.93 | NAAA (0.50) | AGXTIDO1NAAADPP4DPP7 | |
| SCHEMBL11157958 | 0.86 | AGXT (0.53) | AGXTIDO1NAAADPP4DPP7 | |
| SCHEMBL11167252 | 0.84 | KMT2A (0.39) | AGXTIDO1DPP4DPP7FAP | |
| SCHEMBL11007258 | 0.79 | NAAA (0.48) | AGXTNAAADPP4DPP7FAP | |
| SCHEMBL11159698 | 0.78 | IDO1 (0.56) | AGXTIDO1DPP4DPP7FAP | |
| SCHEMBL11002451 | 0.76 | KMT2A (0.40) | AGXTIDO1DPP4DPP7FAP | |
| SCHEMBL11005524 | 0.76 | KMT2A (0.43) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL11010407 | 0.76 | SIGMAR1 (0.44) | NAAADPP4DPP8 | |
| SCHEMBL11006655 | 0.75 | CTSL (0.49) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11008481 | 0.75 | DPP4 (0.42) | NAAADPP4DPP7FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |