Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395367 | 0.92 | PKM (0.61) | PKMSMN1; SMN2CA12CA9ALDH1A1 | |
| SCHEMBL11179269 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11184400 | 0.84 | ALDH1A1 (0.64) | PKMSMN1; SMN2CA12CA9ALDH1A1 | |
| Ethyl Benzoate SCHEMBL23495786 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11261832 | 0.81 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL11251983 | 0.81 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL11257955 | 0.81 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL11266909 | 0.81 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL11272655 | 0.81 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL7782225 | 0.80 | NHERF1 (0.76) | PKMSMN1; SMN2CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411903-A | 4-[(Monosubstituted-alkyl)amino]benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| US-4311846-A | 4-[(Monosubstituted-alkyl) amino]benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4245097-A | 4-[(Monosubstituted-alkyl) amino] benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |