Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178271 | 0.92 | PKM (0.57) | PKMSMN1; SMN2CA12CA9NHERF1 | |
| SCHEMBL7782225 | 0.83 | NHERF1 (0.76) | PKMSMN1; SMN2CA12CA9NHERF1 | |
| SCHEMBL11403189 | 0.83 | ALDH1A1 (0.62) | PKMSMN1; SMN2CA12CA9KMT2A | |
| SCHEMBL11179269 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2AGAANPC1RAB9A | |
| SCHEMBL6673450 | 0.78 | USP2 (0.64) | PKMSMN1; SMN2CA12CA9KMT2A | |
| SCHEMBL11256344 | 0.78 | MAPT (0.69) | SMN1; SMN2KMT2AGAANPC1RAB9A | |
| SCHEMBL7101006 | 0.76 | MAPT (0.60) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL13444627 | 0.76 | LMNA (0.61) | SMN1; SMN2CA12CA9KMT2AGAA | |
| SCHEMBL13028451 | 0.76 | NHERF1 (0.73) | SMN1; SMN2CA12CA9NHERF1KMT2A | |
| SCHEMBL9735670 | 0.76 | HPGD (0.60) | SMN1; SMN2CA12CA9NHERF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281018-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4230628-A | HYPOLIPIDEMIC AGENTS, ANTIATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |