SCHEMBL111786

SCHEMBL111786

CN1CCc2cc(O)c(O)cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.47
▸ DRD1 P21728 5/20 0.44
▸ DRD2 P14416 5/20 0.44
▸ DRD5 P21918 3/20 0.44
▸ DRD4 P21917 2/20 0.44
▸ AR P10275 1/20 0.41
▸ MAPK1 P28482 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ PMP22 Q01453 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ DRD3 P35462 2/20 0.37
▸ NOTUM Q6P988 1/20 0.37
▸ ADCY6 O43306 1/20 0.37
▸ ADCY3 O60266 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803269 1.00 MAOA (0.47) MAOADRD1DRD2DRD5DRD4
Bromide SCHEMBL4625297 0.98 DRD1 (0.47) MAOADRD1DRD2DRD5DRD4
SCHEMBL16900582 0.88 ALDH1A1 (0.49) MAOADRD1DRD2DRD5DRD4
SCHEMBL13957980 0.84 AR (0.40) MAOADRD1DRD2DRD5DRD4
SCHEMBL28104564 0.79 ESR1 (0.35) MAOADRD1DRD2DRD5DRD4
SCHEMBL16687894 0.76 AR (0.41) ARMAPK1THPOHIF1AHSD17B10
SCHEMBL93622 0.75 DRD1 (0.56) DRD1DRD2DRD5DRD4DRD3
SCHEMBL5501377 0.75 DRD2 (0.56) DRD1DRD2DRD5DRD4THPO
SCHEMBL29915622 0.75 MEN1 (0.42) MAOADRD1DRD2DRD5DRD4
SCHEMBL111871 0.75 MEN1 (0.42) MAOADRD1DRD2DRD5DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2026-04-09 — — US claimed
EP-4154864-B1 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR DR KURT WOLFF GMBH & CO KG (DE) 2025-12-17 — — EP claimed
EP-4450054-A2 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR Dr. Kurt Wolff GmbH & Co. KG (DE) 2024-10-23 — — EP claimed
WO-2024205052-A1 COMPOSITION FOR COLORING HAIR 주식회사 엘지생활건강 2024-10-03 — — WO claimed
WO-2024062091-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2024-03-28 — — WO claimed
EP-4154864-A1 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR Dr. Kurt Wolff GmbH & Co. KG (DE) 2023-03-29 — — EP claimed
WO-2021018445-A1 OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR HENKEL AG & CO. KGAA (DE) 2021-02-04 — — WO claimed
EP-2582351-B1 HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT L'ORÉAL (FR) 2017-08-02 — — EP claimed
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 — — EP claimed
EP-2037871-B1 OXIDATION DYES FOR DYEING KERATIN FIBERS CONTAINING ATMOSPHERIC OXYGEN AS THE ONLY OXIDIZING AGENT HENKEL AG & CO KGAA (DE) 2016-02-24 — — EP claimed
WO-1999020234-A1 DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 1999-04-29 — — WO claimed
WO-1999020236-A1 OXIDATION DYEING FOR KERATIN FIBRES L'OREAL (FR) 1999-04-29 — — WO claimed
WO-1999006016-A1 DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-02-11 — — WO claimed
EP-0462857-B2 Dyeing composition containing 5-6 dihydroxyindolines and keratinous fibres dyeing process OREAL (FR) 1998-03-04 — — EP claimed
US-5690697-A COMPOSITION OF AN INDOLE OR INDOLINE COMPOUND, A MANGANESE SALT, A BASIFYING AGENT AND AN OXIDIZER L'OREAL (FR) 1997-11-25 — — US claimed
EP-0697209-B1 Set, process, device and keratineous fibres dyeing composition OREAL (FR) 1996-10-09 — — EP claimed
EP-0697210-B1 Use of a manganese, zinc and/or cobalt salt in a two-steps dyeing process based on an ondole or indoline compound OREAL (FR) 1996-09-25 — — EP claimed
US-5538517-A NONDESTRUCTIVE HAIR DYES L'OREAL (FR) 1996-07-23 — — US claimed
EP-0645999-B1 METHOD FOR DYEING KERATIN FIBRES WITH INDOLE OR INDOLIN DERIVATIVES, HYDROGEN PEROXIDE AND A PEROXIDASE OREAL (FR) 1996-01-31 — — EP claimed
US-5178637-A Hair dyes L'OREAL (FR) 1993-01-12 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR TYR, KRT18, TPH1 MAOA 23/4885DRD1 523/4885DRD2 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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