Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086015 | 1.00 | HCAR2 (0.71) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5598744 | 0.85 | HCAR2 (0.74) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5598741 | 0.85 | HCAR2 (0.74) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL600082 | 0.83 | HCAR2 (1.00) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL143282 | 0.83 | HCAR2 (1.00) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3707176 | 0.83 | — | — | |
| SCHEMBL1862223 | 0.82 | HCAR2 (0.69) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3382206 | 0.82 | HCAR2 (0.69) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20273260 | 0.82 | HCAR2 (0.69) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL369705 | 0.82 | HCAR2 (0.69) | HCAR2ABCG2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1217943-C | New use and novel N-azabicyclo-amide derivatives | ASTRAZENECA AB (SE) | 2005-09-07 | — | — | CN | claimed |
| CN-1423651-A | Novel use and novel N-azabicyclo-amide derivatives | ASTRAZENECA AB (SE) | 2003-06-11 | — | — | CN | claimed |
| US-20200024294-A1 | Organic metal compound and organic light-emitting device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-01-23 | — | — | US | disclosed |
| EP-2573078-B1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-11-02 | — | — | EP | disclosed |
| EP-2573078-B1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-11-02 | — | — | EP | disclosed |
| US-9439881-B2 | Acrylamide compounds and use thereof for inhibiting apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-09-13 | — | — | US | disclosed |
| US-9439881-B2 | Acrylamide compounds and use thereof for inhibiting apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-09-13 | — | — | US | disclosed |
| US-9439881-B2 | Acrylamide compounds and use thereof for inhibiting apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-09-13 | — | — | US | disclosed |
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-02-11 | — | — | US | disclosed |
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-02-11 | — | — | US | disclosed |
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | CHINESE PLA GENERAL HOSPITAL (CN) | 2016-02-11 | — | — | US | disclosed |
| US-20130158022-A1 | Acrylamide Compounds And Use Thereof For Inhibiting Apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2013-06-20 | — | — | US | disclosed |
| US-20130158022-A1 | Acrylamide Compounds And Use Thereof For Inhibiting Apoptosis | CHINESE PLA GENERAL HOSPITAL (CN) | 2013-06-20 | — | — | US | disclosed |
| EP-2573078-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | Chinese PLA General Hospital (CN) | 2013-03-27 | — | — | EP | disclosed |
| EP-2573078-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | Chinese PLA General Hospital (CN) | 2013-03-27 | — | — | EP | disclosed |
| CN-102241673-A | Acrylamide compounds and medicinal uses thereof | CHINESE PLA GENERAL HOSPITAL | 2011-11-16 | — | — | CN | disclosed |
| EP-2233484-A2 | Oxazolidinone derivatives having a 7-membered heterocyclic ring | Research Foundation Itsuu Laboratory (JP) | 2010-09-29 | — | — | EP | disclosed |
| US-20090192180-A1 | Alpha-7 Nicotinic Receptor Agonists and Statins In Combination | KEITH RICHARD | 2009-07-30 | — | — | US | disclosed |
| CN-1217943-C | New use and novel N-azabicyclo-amide derivatives | ASTRAZENECA AB (SE) | 2005-09-07 | — | — | CN | disclosed |
| CN-1423651-A | Novel use and novel N-azabicyclo-amide derivatives | ASTRAZENECA AB (SE) | 2003-06-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038445-A1 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS | BAX, API5, BCL2 | HCAR2 1531/4885ABCG2 283/4885SMN1; SMN2 404/4885 |
| US-20130158022-A1 | Acrylamide Compounds And Use Thereof For Inhibiting Apoptosis | BAX, API5, BCL2 | HCAR2 1531/4885ABCG2 283/4885SMN1; SMN2 404/4885 |
| US-20200024294-A1 | Organic metal compound and organic light-emitting device | ORC3, C1S, C1R | HCAR2 3673/4885ABCG2 3515/4885SMN1; SMN2 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.