Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778467 | 0.89 | TSHR (0.47) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL11189598 | 0.85 | ALDH1A1 (0.41) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL7779646 | 0.82 | TSHR (0.41) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL10027108 | 0.78 | TSHR (0.39) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL10309528 | 0.73 | TSHR (0.38) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL9470186 | 0.73 | CTSK (0.65) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL3635136 | 0.72 | TSHR (0.63) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL2223429 | 0.72 | TSHR (0.63) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL14001946 | 0.71 | ALDH1A1 (0.66) | ALDH1A1POLBHTTSMN1; SMN2TSHR | |
| SCHEMBL675456 | 0.70 | ALDH1A1 (0.61) | ALDH1A1POLBHTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4406689-A | Certain aralkyloxy or thio-pyridyl-imidazo-pyridines and their herbicidal use | ZOECON CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |