Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327643 | 0.95 | — | — | |
| SCHEMBL31074229 | 0.77 | CES2 (0.56) | — | |
| Thiophene Carboxylic Acid SCHEMBL30100986 | 0.76 | — | — | |
| SCHEMBL1650092 | 0.75 | — | — | |
| SCHEMBL2906402 | 0.73 | — | — | |
| SCHEMBL20067208 | 0.73 | — | — | |
| SCHEMBL468077 | 0.73 | — | — | |
| SCHEMBL11521389 | 0.73 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL11452199 | 0.71 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL10898175 | 0.71 | CES2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | disclosed |