SCHEMBL11194367

SCHEMBL11194367

O=[N+]([O-])C1=CC(Cl)=CC[CH]1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL378762 0.80
SCHEMBL9295399 0.79 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL4432674 0.75
SCHEMBL970308 0.75
SCHEMBL10957830 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL4600069 0.67 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9936989 0.67 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL6823381 0.67 ACHE (0.31) ALDH1A1TSHR
SCHEMBL4272720 0.63 VCAM1 (0.33)
SCHEMBL4279071 0.63 CASP6 (0.34) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087392-A2 Cyanacyl amide derivatives and preparation thereof CIBA-GEIGY AG (CH) 1983-08-31 EP disclosed
EP-0087394-A2 Process for the preparation of N-substituted N-cyano-amides and their use CIBA-GEIGY AG (CH) 1983-08-31 EP disclosed