SCHEMBL378762

SCHEMBL378762

O=[N+]([O-])C1=CC([N+](=O)[O-])=CC[CH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9936989 0.80 ALDH1A1 (0.30)
SCHEMBL4432674 0.80
SCHEMBL9295399 0.80 ALDH1A1 (0.34)
SCHEMBL970308 0.80
SCHEMBL4600069 0.80 ALDH1A1 (0.31)
SCHEMBL11194367 0.80 ALDH1A1 (0.30)
SCHEMBL6823381 0.80 ACHE (0.31)
SCHEMBL4279071 0.76 CASP6 (0.34)
SCHEMBL4272720 0.76 VCAM1 (0.33)
SCHEMBL15288773 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622280-B2 Emulsion compositions 454 LIFE SCIENCES CORPORATION (US) 2009-11-24 US claimed
EP-1518937-B1 Increasing the concentration of a nucleic acid molecule MEDICAL RES COUNCIL (GB) 2007-09-05 EP claimed
EP-1518937-A1 Increasing the concentration of a nucleic acid molecule MEDICAL RESEARCH COUNCIL (GB) 2005-03-30 EP claimed
US-20050064460-A1 Emulsion compositions MEDICAL RESEARCH COUNCIL 2005-03-24 US claimed
EP-1347301-A1 METHOD FOR ULTRA-RAPID AND ULTRA-SENSITIVE MEASUREMENT International Reagents Corporation (JP) 2003-09-24 EP claimed
US-5405950-A N4 -substituted cytidines and process for incorporation into an oligonucleotides AMOCO CORPORATION (US) 1995-04-11 US claimed
CN-114751920-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-114736219-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
US-20240166666-A1 ANTITUMORAL COMPOUNDS PHARMA MAR SA (ES) 2024-05-23 US disclosed
CN-117986153-A Ionizable cationic lipid compound, and preparation method and application thereof 晟迪生物医药(苏州)有限公司 2024-05-07 CN disclosed
EP-3604385-B1 HETEROBIFUNCTIONAL MONODISPERSED POLYETHYLENE GLYCOL AND CONJUGATE USING THE SAME NOF CORP (JP) 2024-05-01 EP disclosed
US-20240131180-A1 DRUG ANTIBODY CONJUGATES PHARMA MAR, S.A. (ES) 2024-04-25 US disclosed
CN-117865987-A Antitumor compounds 法马马有限公司 2024-04-12 CN disclosed
EP-0222889-A4 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1988-09-28 EP disclosed
US-4676980-A A HETEROAGGREGATE ABLE TO BIND TO BOTH A CYTOTOXIC CELL AND CELL TO BE LYSED; ANTITUMOR AND CARCINOGENIC AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1987-06-30 US disclosed
EP-0222889-A1 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1987-05-27 EP disclosed
EP-0217688-A1 Peptide derivatives with a lactonic or cycloamidic structure, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1987-04-08 EP disclosed
US-4629688-A CLINICAL ANALYSIS MILES LABORATORIES, INC. (US) 1986-12-16 US disclosed
WO-1986006726-A1 CYTIDINE ANALOGS INTEGRATED GENETICS, INC. (US) 1986-11-20 WO disclosed
US-4383031-A LIGANDS; IMMUNOASSAY; SIMPLIFICATION; DIAGNOSIS/MEDICAL/ MILES LABORATORIES, INC. (US) 1983-05-10 US disclosed