SCHEMBL11197847

SCHEMBL11197847

O=C=Nc1ccc(S(=O)(=O)c2ccc(N=C=O)c(O)c2)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
MAPT P10636 1/20 0.44
POLB P06746 2/20 0.38
SERPINE1 P05121 2/20 0.36
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 3/20 0.36
HPGD P15428 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSD17B10 Q99714 2/20 0.35
PTGS1 P23219 2/20 0.35
PTGS2 P35354 2/20 0.35
TRPA1 O75762 1/20 0.34
PTPN1 P18031 2/20 0.34
DUSP5 Q16690 1/20 0.34
CA2 P00918 4/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11194024 0.79 RAD1 (0.36) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL11194630 0.78 MAPK1 (0.40) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL11191599 0.78 CYP3A4 (0.46) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL739692 0.74 CYP3A4 (0.59) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL739522 0.74 MAPK1 (0.44) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL6901481 0.73 TRPA1 (0.46) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL11188213 0.72 CYP3A4 (0.37) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL11198992 0.72 SIRT1 (0.40) GAAMAPTPOLBALDH1A1CYP3A4
SCHEMBL11193524 0.72 CYP3A4 (0.41) ALDH1A1CYP3A4HPGDTDP1TRPA1
SCHEMBL27572436 0.71 CYP3A4 (0.43) GAAMAPTALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4421905-A METAL ACETYLACETONATE AS POLYMERIZATION CATALYSTS PLASTICS ENGINEERING COMPANY (US) 1983-12-20 US disclosed