Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157483 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4ALOX15TRPA1 | |
| SCHEMBL79979 | 0.84 | MEN1 (0.41) | ALDH1A1HPGDCYP3A4ALOX15ACHE | |
| SCHEMBL3262579 | 0.74 | TRPA1 (0.41) | ALDH1A1HPGDTRPA1ACHEL3MBTL1 | |
| SCHEMBL3494510 | 0.74 | TSHR (0.38) | ALDH1A1HPGDCYP3A4ALOX15L3MBTL1 | |
| SCHEMBL3956783 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP3A4ALOX15L3MBTL1 | |
| SCHEMBL10639464 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDCYP3A4ALOX15TRPA1 | |
| SCHEMBL10351891 | 0.72 | MEN1 (0.48) | ALDH1A1HPGDCYP3A4ALOX15TRPA1 | |
| SCHEMBL10430629 | 0.72 | L3MBTL1 (0.34) | ALDH1A1HPGDALOX15ACHEL3MBTL1 | |
| Diallyldisulfide SCHEMBL28956854 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4ALOX15TRPA1 | |
| Diallyldisulfide SCHEMBL668587 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4ALOX15TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394476-A | POLYMERS, BUTADIENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4394476-A | POLYMERS, BUTADIENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0060799-A1 | Diester antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0060799-A1 | Diester antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |