SCHEMBL11198547

SCHEMBL11198547

C=CCSc1cccc(O)c1S

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ACHE P22303 2/20 0.32
LMNA P02545 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10639464 0.81 ALDH1A1 (0.41) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL79979 0.81 MEN1 (0.41) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10430629 0.80 L3MBTL1 (0.34) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL3262579 0.79 TRPA1 (0.41) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL6588281 0.77 MAPK1 (0.37) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10639474 0.75 L3MBTL1 (0.38) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10351891 0.74 MEN1 (0.48) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL27233210 0.72 L3MBTL1 (0.41) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL11198541 0.70 ALDH1A1 (0.37) MAPK1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL27233182 0.69 L3MBTL1 (0.39) MAPK1ALDH1A1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4394476-A POLYMERS, BUTADIENE-STYRENE COPOLYMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-19 US disclosed
US-4394476-A POLYMERS, BUTADIENE-STYRENE COPOLYMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-19 US disclosed
EP-0060799-A1 Diester antioxidants THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-09-22 EP disclosed
EP-0060799-A1 Diester antioxidants THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-09-22 EP disclosed