Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689118 | 0.85 | TACR1 (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL14488100 | 0.85 | TACR1 (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL17039822 | 0.85 | TACR1 (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL1001807 | 0.84 | FAAH (0.55) | ACEACE2ITGB3ITGA2B | |
| SCHEMBL14969565 | 0.84 | TACR1 (0.55) | CTSKCTSSPOLB | |
| SCHEMBL8618495 | 0.83 | CTSK (0.38) | ACEACE2CTSKCTSLCTSS | |
| SCHEMBL11285763 | 0.83 | CTSL (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4385669 | 0.82 | POLB (0.62) | ACEACE2CTSKPOLBTSHR | |
| SCHEMBL3652453 | 0.82 | POLB (0.62) | ACEACE2CTSKPOLBTSHR | |
| SCHEMBL6544705 | 0.82 | NMBR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080305-A1 | Antiviral 2'-deoxyuridines, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-06-01 | — | — | EP | disclosed |