Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5874939 | 0.92 | TLR2 (0.40) | ITGB3ITGA2BHRH3 | |
| SCHEMBL11567871 | 0.89 | L3MBTL1 (0.37) | ITGB3ITGA2BHRH3HRH4HPGD | |
| SCHEMBL5880046 | 0.89 | TAS1R3 (0.39) | CTSKTAS1R3TAS1R1SMN1; SMN2NPC1 | |
| SCHEMBL29973774 | 0.87 | TAS1R3 (0.39) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL5492142 | 0.85 | TAS1R3 (0.39) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL8617019 | 0.85 | CTSK (0.52) | CTSKCTSLCTSS | |
| SCHEMBL7320186 | 0.84 | SMN1; SMN2 (0.40) | HRH3HRH4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30804479 | 0.84 | TAS1R3 (0.40) | TAS1R3TAS1R1L3MBTL1KMT2A | |
| SCHEMBL11199811 | 0.83 | ACE (0.52) | CTSKITGB3ITGA2BCTSLCTSS | |
| SCHEMBL11285763 | 0.83 | CTSL (0.59) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |