Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11142346 | 0.88 | THRB (0.40) | ALDH1A1L3MBTL1KDM4EGFERHSP90AA1 | |
| SCHEMBL11200342 | 0.85 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1KDM4EGFERSMN1; SMN2 | |
| SCHEMBL20932207 | 0.84 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1KDM4EGFERMEN1 | |
| SCHEMBL11187062 | 0.82 | SLC18A3 (0.44) | ALDH1A1L3MBTL1KDM4EGFERHTT | |
| SCHEMBL4061177 | 0.82 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1KDM4EGFERMEN1 | |
| SCHEMBL2956428 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1HSP90AA1NTSR1HTT | |
| SCHEMBL13099907 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1HSP90AA1NTSR1HTT | |
| SCHEMBL3228765 | 0.81 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KDM4EGFERHSP90AA1 | |
| Hydrochloric Acid SCHEMBL29086343 | 0.81 | HSP90AA1 (0.47) | ALDH1A1L3MBTL1KDM4EHSP90AA1NTSR1 | |
| Hydrochloric Acid SCHEMBL29488818 | 0.81 | HSP90AA1 (0.47) | ALDH1A1L3MBTL1KDM4EHSP90AA1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122180-A1 | PYRIMIDINE DERIVATIVES CAPABLE OF INHIBITING ONE OR MORE KINASES | MEDICAL RESEARCH COUNCIL (GB) | 2009-10-08 | — | — | WO | disclosed |
| US-4417052-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; VIRICIDES | STERLING DRUG INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4308382-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4216326-A | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1980-08-05 | — | — | US | disclosed |
| US-4069256-A | Anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1978-01-17 | — | — | US | disclosed |