SCHEMBL11200488

SCHEMBL11200488

[c]1nc2c(-c3cccc4snnc34)cccc2s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411212 0.86
SCHEMBL16714174 0.75 TDO2 (0.40)
SCHEMBL4337978 0.75 LIMK1 (0.39)
SCHEMBL7754182 0.73 KDM4E (0.37)
SCHEMBL14761693 0.73
SCHEMBL29039582 0.72 HPGD (0.36)
SCHEMBL21351983 0.72
SCHEMBL29039588 0.71 ALDH1A1 (0.37)
SCHEMBL16150637 0.71 NOTUM (0.38)
SCHEMBL6509472 0.71 MAPT (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0088454-A2 New starting compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-14 EP disclosed
EP-0025199-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-03-18 EP disclosed