Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862612 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL4855491 | 0.81 | BCAT2 (0.64) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL18204441 | 0.79 | MTNR1A (0.58) | SMN1; SMN2RAB9ANPC1MTNR1AMTNR1B | |
| SCHEMBL15671577 | 0.78 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL7090783 | 0.76 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL2427167 | 0.75 | CNR1 (0.70) | CNR1MTNR1AMTNR1BCNR2EPHX2 | |
| SCHEMBL8943316 | 0.75 | TGM2 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1MTNR1A | |
| Hydrochloric Acid SCHEMBL4890327 | 0.74 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL5455431 | 0.72 | CNR1 (0.57) | ALDH1A1SMN1; SMN2HTTNCOA1NCOA3 | |
| SCHEMBL11627441 | 0.72 | CNR1 (0.46) | ALDH1A1SMN1; SMN2CNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394520-A | SKIN DISORDERS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-07-19 | — | — | US | disclosed |
| US-4204064-A | FOR TREATMENT OF SKIN OR SCALP | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4085217-A | DERIVATIVES OF CYSTEINE OR CYSTEAMINE | L'OREAL (FR) | 1978-04-18 | — | — | US | disclosed |
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | disclosed |