Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431214 | 0.83 | MTNR1A (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11365927 | 0.81 | KMT2A (0.46) | SMN1; SMN2F2RL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11206453 | 0.79 | KMT2A (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11204042 | 0.78 | POLB (0.37) | SMN1; SMN2KMT2AMEN1POLBGLA | |
| SCHEMBL11210933 | 0.78 | KMT2A (0.41) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11210936 | 0.77 | NAAA (0.40) | ALDH1A1 | |
| SCHEMBL11265051 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2F2RL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11290034 | 0.76 | TSHR (0.37) | SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL11208710 | 0.76 | LMNA (0.42) | KMT2AMEN1ACACB | |
| SCHEMBL11018542 | 0.74 | KDM4E (0.38) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |