Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ESRRB | O95718 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204042 | 0.85 | POLB (0.37) | LMNAACACBMEN1KMT2AL3MBTL1 | |
| SCHEMBL11210933 | 0.84 | KMT2A (0.41) | EPHX2KMT2A | |
| SCHEMBL11210936 | 0.81 | NAAA (0.40) | — | |
| SCHEMBL11267481 | 0.80 | LMNA (0.44) | LMNAESRRGNR1H4SIGMAR1S1PR1 | |
| SCHEMBL11210382 | 0.79 | TSHR (0.44) | MEN1KMT2ATRPV1 | |
| SCHEMBL11201248 | 0.76 | SMN1; SMN2 (0.52) | ACACBMEN1KMT2A | |
| SCHEMBL11018542 | 0.75 | KDM4E (0.38) | LMNAMEN1KMT2ACA1CA2 | |
| SCHEMBL11018732 | 0.75 | RAB9A (0.37) | LMNARAB9AMEN1KMT2A | |
| SCHEMBL11205749 | 0.74 | CTDSP1 (0.38) | LMNAMEN1KMT2A | |
| SCHEMBL11208506 | 0.74 | PPARA (0.37) | LMNAS1PR1ACACBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |